ABSTRACT
Background: Maternal anaemia is a common problem worldwide. The aim of this study is to compare the efficacy and safety of FCM vs iron sucrose for correction of iron deficiency during pregnancy.Methods: This study was conducted in Swasthya healthcare, Jammu for a period of ten months from Sep 2017 to June 2018. A total of 100 women with Hb 7-9.9g% enrolled. They were divided into two groups of 50 each. Group A were given Iron Carboxy maltose and Group B were given Iron Sucrose. These were compared for their efficacy and safety.Results: In the present study, the rise in mean hemoglobin at 4 weeks in Group A was 1.79±0.47 and 1.06±0.11 in Group B which was highly significant (p-value<0.0001). Rise in mean serum ferritin level at 4 weeks in Group A was 123.80±16.03 and in Group B was 84.78±10.53. Statistically, this rise was also highly significant (p<0.0001). In present study, adverse reactions were observed in 34% patients in Group A, while in Group B it was observed in 52% patients.Conclusions: Iron carboxy maltose shows higher rise in hemoglobin and ferritin levels as compared to Iron Sucrose and incidence of adverse effects is also comparatively lower in the former.
ABSTRACT
Post partum cerebral venous sinus thrombosis (CVT) in a high risk predisposed individual and its management particularly after a major surgical intervention i.e. lower segment caesarean section (LSCS) is debatable. Guidelines are there to treat after 72 hours of major surgical intervention. We report a case of CVT with generalised tonic clonic seizures as a life threatening complication in whom anticoagulation was started at 48 hours post LSCS without any complications of anticoagulation. We recommend early anticoagulation despite major surgical intervention, so as to avoid the impending life threatening complications following cerebral venous thrombosis in predisposed individuals.